Parkinson’s disease (PD) is a progressive neurodegenerative disorder, which means it’s a condition that affects your brain and its symptoms increase over time. While Parkinson’s disease is often recognized for its effects on movement, balance, and muscle control, it can also impact many other functions of the nervous system. These include memory, thinking, mental health, as well as digestive, urinary and sensory functions.
More than a million people in the US live with Parkinson’s disease, and nearly 100,000 new cases are diagnosed each year. PD is most commonly diagnosed in those over 65 years old, but can be diagnosed as early as your 20s and as late as your 80s or beyond.
While most people associate PD with tremors (shaking), this symptom affects only a little more than half of people with the condition. The main symptoms that affect everyone with PD is that over time it makes everyday movements slower and more difficult. Other motor symptoms that can occur with PD include rigidity (muscle stiffness), trouble walking and balance problems.
Parkinson’s happens when a protein called alpha-synuclein clumps in certain areas of the brain, reducing dopamine—a chemical that helps control movement. As dopamine levels drop, movement becomes harder, but symptoms vary from person to person.
The good news is that research is making progress. Scientists have discovered genes linked to Parkinson’s disease and are learning more about the chemical changes in the brain that cause it. These breakthroughs are leading to new treatment possibilities and hope for better ways to manage—and maybe even someday cure—the condition.